Poly (1,2 - dihydro - 2,2,4 - trimethylquinoline)
RTECS #: TQ2625000
CAS #: 26780-96-1
UPDATE: July 2000 MW: N/R MF: (C12H15N)x
NOTE:
TOXICITY DATA HAVE NOT BEEN EVALUATED. OMISSION OF A SUBSTANCE OR NOTATION DOES NOT IMPLY ANY RELIEF FROM REGULATORY RESPONSIBILITY.
SYNONYMS:
Nonflex RD
Nocrac 224
2,2,4 - Trimethyl - 1,2 - dihydroquinoline polymer
Trimethyldihydroquinoline polymer
Flectol Flakes
Vulkanox HS
Vanlube RD
Ultranox 254
Ryphosan S
Quinoline, 1,2 - dihydro - 2,2,4 - trimethyl - , homopolymer
Poly (2,2,4 - trimethyl - 1,2 - dihydroquinoline)
Poly (1,2 - dihydro - 2,2,4 - trimethylquinoline)
Naugard Super Q
HS (antioxidant)
Forte RD
Flectol TMQ
1,2 - Dihydro - 2,2,4 - trimethylquinoline polymer
Polnoks R
Vulkanox HS - LG
Flectol H, polymer
Antioxidant HS
Antioxidant HSL
Antigene RDF
Permanax 45
Permanax TQ
Acetonanil
Agerite MA
REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT
REFERENCE
oral
rat lowest published toxic dose: 6,700 mg/kg (6-15 day pregnant) Reproductive:
Maternal effects: Ovaries, fallopian tubes
Reproductive: Other effects on female
Reproductive: Effects on fertility: Post- implantation mortality (e.g.,
dead and/or resorbed implants per total number of implants) TCMUD8 16,75,1996
oral
rat lowest published toxic dose: 6,700 mg/kg (6-15 day pregnant) Reproductive:
Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)
Reproductive: Specific developmental abnormalities: Central nervous system
Reproductive: Specific developmental abnormalities: Urogenital system TCMUD8
16,75,1996
oral
rat lowest published toxic dose: 3,400 mg/kg (6-15 day pregnant) Reproductive:
Specific developmental abnormalities: Musculoskeletal system TCMUD8 16,75,1996
TUMORIGENIC DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT
REFERENCE
oral
rat lowest published toxic dose: 548 gm/kg/2 year- continuous Tumorigenic:
Neoplastic by RTECS criteria
Blood: Lymphoma including Hodgkin's disease TXAPA9 9,583,1966
ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT
REFERENCE
oral
rat lowest published toxic dose: 2,680 mg/kg N/R TCMUD8 16,1975,1996
OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT
REFERENCE
oral
rat lowest published toxic dose: 6,300 mg/kg/6 week- continuous Behavioral:
Food intake (animal)
Liver: Liver function tests impaired
Liver: Changes in liver weight NTIS** OTS0545812
STANDARDS AND REGULATIONS:
ORGANIZATION STANDARD
REFERENCE
Occupational Exposure Limit - RUSSIA short term exposure limit 1 mg/m3, JAN1993
NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey
1974: Hazard Code: 83321;
Number of Industries 30;
Total Number of Facilities 1,799;
Number of Occupations 34;
Total Number of Employees Exposed 21,389
National Occupational Exposure Survey 1983 National Occupational Exposure
Survey 1983: Hazard Code: X9284;
Number of Industries 57;
Total Number of Facilities 4,693;
Number of Occupations 51;
Total Number of Employees Exposed 101,343;
Total Number of Female Employees Exposed 12,693
STATUS IN FEDERAL AGENCIES:
ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(e) Risk Notification, 8EHQ-0293-8715;8EHQ-0892-9297
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
REFERENCES:
CODEN
REFERENCE
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly
U.S. Clearinghouse for Scientific & Technical Information.
TCMUD8 Teratogenesis, Carcinogenesis, and Mutagenesis. (Alan R. Liss, Inc.,
41 E. 11th St., New York, NY 10003) V.1- 1980-
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First
St., Duluth, MN 55802) V.1- 1959-
RTECS Compound Description:
Tumorigen
Reproductive Effector
ALT CAS #: 52038-43-4
ALT CAS #: 55069-42-6